#################################################### # Disordered Binding Sites (DIBS) database # # Version: 28-09-2017 # # Source: http://dibs.enzim.ttk.mta.hu/ # #################################################### Format definition for the downloadable version of DIBS (DIBS_complete.txt). Entries are separated by empty lines. Each entry consists of several lines, each of which starts with a [tag], followed by an equal sign (=), followed by the actual value. While most tags are present for every entry, some are optional. The definition of various data and their corresponding tags are listed below. [Entry] - Start of the entry. [Accession] - DIBS database accession. Consists of the characters 'DI' followed by 7 digits. [Disorder status] - Type of evidence for the disordered nature of the interacting protein. Can be 'Confirmed', 'Inferred from homology' or 'Inferred from motif'. [Kd] - Dissociation constant of the interaction, if known. [Name] - A short description of the protein complex presented in the entry. [Source organism] - The list of organisms from which the constituent protein chains originate. [PDB ID] - ID of the PDB structure describing the complex. [PDB chain IDs] - The list of IDs for chains in the PDB structure that take part in the described interaction. The first chain ID marks the disordered protein, separated from ordered protein chain ID(s) by a colon. [PDB note] - A description of the transformations made on the referred PDB structure to properly display the biologically relevant, core interaction. These transformations can be the omission of protein chains (to reduce possible duplicity present in the PDB structure), the generation of protein chains (based on the biomatrices described in the PDB file), or truncations of protein chains (to only include regions of proteins that mediate the highlighted interaction). [PDB experimental technique] - Experimental technique used to determine the structure described in the PDB. Can be 'X-ray' or NMR. [PDB resolution] - The resolution of the corresponding PDB structure in Angstom units (optional - only present if the experimental technique is X-ray). [Domain] - Domain type of the ordered partner(s). [Evidence chain X] - Description of and reference(s) to the exerimental work(s) that demonstrate that the region of chain X that is involved in the interaction is intrinsically disordered or ordered (depending on protein type). [Modified residues chain X] - Description of the modified/non-standard residues in the disordered protein chain. If there are several such residues, their description is delimited by '|'. Residue numbering is according to the UniProt sequence numbering. [Chain X name] - The name of the protein with chain ID X (as defined in UniProt). [Chain X source organism] - The organism from which the protein with chain ID X originates. [Chain X UniProt accession] - UniProt accession of the protein with chain ID X. [Chain X UniProt boundaries] - The region of the UniProt sequence that is involved in the interation. [Chain X UniProt coverage] - The fraction of the UniProt sequence that is involved in the interation. [Chain X UniRef90 accession] - The UniRef90 cluster to which the protein with chain ID X belongs. [Chain X UniRef90 boundaries] - The region of the representative UniRef90 sequence that corresponds to the protein region with chain ID X involved in the interation. [Related structures] - PDB IDs of structures that contain interactions that are highly similar to the one described in the entry (for a detailed description of what qualifies as 'highly similar' see the Help section at the DIBS website. This field is optional and is omitted if there are no such related structures.